Product Portfolio

Pain and Inflammation

Inflammation is a process by which the body’s white blood cells and the substances they produce protect us from infection with foreign organisms, such as bacteria and viruses. In some diseases, like arthritis, the body’s defense system – the immune system – may trigger an inflammatory response. In these diseases, i.e. autoimmune diseases, the body’s normally protective immune system causes damage to its own tissues. The body responds as if normal tissues are infected or somehow abnormal.

Osteoarthritis is a quite frequent condition in which one or more joints are affected by a degenerative process which, over time, leads to a progressive loss of the normal function. Pain – due to the concurrent onset of inflammation – is the main symptom associated with this condition. Osteoarthritis involves the breakdown of cartilage. Normal cartilage protects a joint and allows it to move smoothly. Cartilage also absorbs shock when pressure is placed on the joint, such as while walking. Without the normal amount of cartilage, the bones rub together. This causes swelling (inflammation) and stiffness.

Pain may not be a primary issue but can be a life-disrupting symptom of an inflammatory disease, since many organs do not have many pain-sensitive nerves. Treatment of organ inflammation is directed at the cause of inflammation whenever possible, while relieving the most disrupting symptoms for the patient.

Pain and Inflammation products

Dona/Viartril

Dona (Glucosamine sulfate) is an osteoarthritis treatment drug that acts through the modulation of cytokines, mediators of the biological genesis of the arthritis process, resulting, among other things, in the stimulation of the cartilage metabolism, joint protection, as well as reducing pain over time and supporting joint mobility. The brand name family of Dona includes Viartril, Arthril, DONArot, Artrofort, Xicil and Osaflexan. Two long-term clinical studies have shown that Dona is able to delay the progression of knee osteoarthritis and a 6-month study performed according to the EMA rules, assessed its role as a symptomatic slow-acting drug for osteoarthritis (SYSADOA). It has been suggested as a first line treatment and basic therapy for the management of knee osteoarthritis by the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).

Reparil

Reparil is used for the treatment of traumatic injuries, edema and venous diseases. Reparil is clinically proven to relieve pain rapidly due to its anti-inflammatory effect. The natural extract inside contributes to reduce edema, a condition often present during trauma and in venous diseases. The Reparil product family includes various brands such as Reparil Gel, Feparil and Venoparil for topical treatment and also an oral form (Reparil dragees).

GO-ON

GO-ON is a product based on hyaluronic acid injected intra-articularly, used for the treatment of osteoarthritis of the knee and other joints such as shoulder, hand and hip. It is classed as a medical device. The hyaluronic acid is derived from a biosynthetic source and the highly standardized purification process guarantees absence of immunogenic reactions and avian virus contamination. GO-ON does not contain any animal protein or exogenous DNA.

Rheumon

Rheumon (Etofenamate) is a non-steroidal anti- inflammatory drug (NSAID) for topical or intra-muscular administration. NSAIDs relieve pain and reduce the inflammation and fever produced by the body’s immune system. Etofenamate has been successfully used for a number of years to treat patients with acute or chronic rheumatic diseases.

Other pain and inflammation products

Axorid

Difflam

Lederspan

Rantudil

Relifex

Soma

Tilcotil

Zamadol

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